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1

The plasma pharmacokinetics and cerebral spinal fluid penetration of intravenous topiramate in newborn pigs

Jeffrey L. Galinkin, C. Dean Kurth, Heng Shi, Margaret A. Priestley, Andreas W. Loepke, Peter C. Adamson

Journal:

Biopharmaceutics & Drug Disposition

Year:

2004

Language:

english

File:

PDF, 94 KB

english, 2004

2

Structural plasticity of dentate granule cell mossy fibers during the development of limbic epilepsy

Steve C. Danzer, Xiaoping He, Andreas W. Loepke, James O. McNamara

Journal:

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

3

The plasma and CSF pharmacokinetics of intravenous topiramate in neonatal pigs

Galinkin, J. L., Kurth, C. D., Priestley, M. A., Loepke, A. W., Adamson, P. C.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2003

Language:

english

File:

PDF, 96 KB

english, 2003

4

Outcome for the extremely premature neonate: how far do we push the edge?

Anne C. Boat, Senthilkumar Sadhasivam, Andreas W. Loepke, Charles D. Kurth

Journal:

Pediatric Anesthesia

Year:

2011

Language:

english

File:

PDF, 143 KB

english, 2011

5

Anesthesia during surgical repair for congenital heart disease and the developing brain: neurotoxic or neuroprotective?

Lisa Wise-Faberowski, Andreas Loepke

Journal:

Pediatric Anesthesia

Year:

2011

Language:

english

File:

PDF, 144 KB

english, 2011

6

An Assessment of the Effects of General Anesthetics on Developing Brain Structure and Neurocognitive Function

Loepke, Andreas W., Soriano, Sulpicio G.

Journal:

Anesthesia & Analgesia

Year:

2008

Language:

english

File:

PDF, 506 KB

english, 2008

7

The impact of the perioperative period on neurocognitive development, with a focus on pharmacological concerns

George K. Istaphanous, Christopher G. Ward, Andreas W. Loepke

Journal:

Best Practice & Research Clinical Anaesthesiology

Year:

2010

Language:

english

File:

PDF, 310 KB

english, 2010

8

Abnormalities of granule cell dendritic structure are a prominent feature of the intrahippocampal kainic acid model of epilepsy despite reduced postinjury neurogenesis

Brian L. Murphy, Rylon D. Hofacer, Christian N. Faulkner, Andreas W. Loepke, Steve C. Danzer

Journal:

Year:

2012

Language:

english

File:

PDF, 2.29 MB

english, 2012

9

Contributions of mature granule cells to structural plasticity in temporal lobe epilepsy

V.R. Santos, O.W. de Castro, R.Y.K. Pun, M.S. Hester, B.L. Murphy, A.W. Loepke, N. Garcia-Cairasco, S.C. Danzer

Journal:

Year:

2011

Language:

english

File:

PDF, 2.19 MB

english, 2011

10

Anesthetics and sedatives: Toxic or protective for the developing brain?

Christopher G. Ward, Andreas W. Loepke

Journal:

Pharmacological Research

Year:

2012

Language:

english

File:

PDF, 175 KB

english, 2012

11

Cell age-specific vulnerability of neurons to anesthetic toxicity

Hofacer, Rylon D., Deng, Meng, Ward, Christopher G., Joseph, Bernadin, Hughes, Elizabeth A., Jiang, Connie, Danzer, Steve C., Loepke, Andreas W.

Journal:

Annals of Neurology

Year:

2013

Language:

english

File:

PDF, 693 KB

english, 2013

12

Brain regional vulnerability to anaesthesia-induced neuroapoptosis shifts with age at exposure and extends into adulthood for some regions

Deng, M., Hofacer, R. D., Jiang, C., Joseph, B., Hughes, E. A., Jia, B., Danzer, S. C., Loepke, A. W.

Journal:

British Journal of Anaesthesia

Year:

2014

Language:

english

File:

PDF, 1.54 MB

english, 2014

13

Development and validation of a multiwavelength spatial domain near-infrared oximeter to detect cerebral hypoxia-ischemia

Nelson, Lindsey A., McCann, John C., Loepke, Andres W., Wu, Jun, Dor, Baruch Ben, Kurth, C. Dean

Journal:

Journal of Biomedical Optics

Year:

2006

Language:

english

File:

PDF, 339 KB

english, 2006

14

Anesthetic Neurotoxicity

Lin, Erica P., Soriano, Sulpicio G., Loepke, Andreas W.

Journal:

Anesthesiology Clinics

Year:

2014

Language:

english

File:

PDF, 227 KB

english, 2014

15

Patient and procedural characteristics for successful and failed immediate tracheal extubation in the operating room following cardiac surgery in infancy

Miller, Jeffrey W., Vu, Dien, Chai, Paul J., Kreutzer, Janet, Hossain, Md M., Jacobs, Jeffrey P., Loepke, Andreas W., Hammer, Greg

Journal:

Pediatric Anesthesia

Year:

2014

Language:

english

File:

PDF, 209 KB

english, 2014

16

Heterogeneous Integration of Adult-Generated Granule Cells into the Epileptic Brain

Murphy, B. L., Pun, R. Y. K., Yin, H., Faulkner, C. R., Loepke, A. W., Danzer, S. C.

Journal:

Journal of Neuroscience

Year:

2011

Language:

english

File:

PDF, 4.35 MB

english, 2011

17

Anesthesia and the developing brain: a way forward for clinical research

Davidson, Andrew J., Becke, Karin, de Graaff, Jurgen, Giribaldi, Gaia, Habre, Walid, Hansen, Tom, Hunt, Rodney W., Ing, Caleb, Loepke, Andreas, McCann, Mary Ellen, Ormond, Gillian D., Pini Prato, Ales

Journal:

Pediatric Anesthesia

Year:

2015

Language:

english

File:

PDF, 146 KB

english, 2015

18

Clinical Research Into Anesthetic Neurotoxicity

Lei, Susan Y., Hache, Manon, Loepke, Andreas W.

Journal:

Journal of Neurosurgical Anesthesiology

Year:

2014

Language:

english

File:

PDF, 156 KB

english, 2014

19

Preclinical Research Into the Effects of Anesthetics on the Developing Brain

Mintz, Cyrus David, Wagner, Meredith, Loepke, Andreas W.

Journal:

Journal of Neurosurgical Anesthesiology

Year:

2012

Language:

english

File:

PDF, 131 KB

english, 2012

20

Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar

Jevtovic-Todorovic, V., Absalom, A. R., Blomgren, K., Brambrink, A., Crosby, G., Culley, D. J., Fiskum, G., Giffard, R. G., Herold, K. F., Loepke, A. W., Ma, D., Orser, B. A., Planel, E., Slikker, W.,

Journal:

BJA British Journal of Anaesthesia

Year:

2013

Language:

english

File:

PDF, 306 KB

english, 2013

21

Anesthetics and the Developing Brain: The Yin and Yang

Lin, Erica P., Lee, Jeong-Rim, Loepke, Andreas W.

Journal:

Current Anesthesiology Reports

Year:

2015

Language:

english

File:

PDF, 259 KB

english, 2015

22

Developmental stage-dependent impact of midazolam on calbindin, calretinin and parvalbumin expression in the immature rat medial prefrontal cortex during the brain growth spurt

Osterop, Samira F., Virtanen, Mari A., Loepke, Johanna R., Joseph, Bernadin, Loepke, Andreas W., Vutskits, Laszlo

Journal:

International Journal of Developmental Neuroscience

Year:

2015

Language:

english

File:

PDF, 2.03 MB

english, 2015

23

Comparison of Ropivacaine 0.2% and Lidocaine 0.5% for Intravenous Regional Anesthesia in Volunteers

Hartmannsgruber, Maximilian W. B., Silverman, David G., Halaszynski, Thomas M., Bobart, Vonda, Brull, Sorin J., Wilkerson, Carlos, Loepke, Andreas W., Atanassoff, Peter G.

Journal:

Anesthesia & Analgesia

Year:

1999

Language:

english

File:

PDF, 183 KB

english, 1999

24

Single surgical procedure with general anaesthesia early in life is associated with subsequent impaired language development and cognitive function

Journal:

Evidence-Based Medicine

Year:

2013

Language:

english

File:

PDF, 45 KB

english, 2013

25

Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia

Backeljauw, B., Holland, S. K., Altaye, M., Loepke, A. W.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

26

Dosing and efficacy of intranasal dexmedetomidine sedation for pediatric transthoracic echocardiography: a retrospective study

Miller, Jeffrey W., Divanovic, Allison A., Hossain, Md M., Mahmoud, Mohamed A., Loepke, Andreas W.

Journal:

Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Year:

2016

Language:

english

File:

PDF, 485 KB

english, 2016

27

Characterization and Quantification of Isoflurane-Induced Developmental Apoptotic Cell Death in Mouse Cerebral Cortex

Istaphanous, George K., Ward, Christopher G., Nan, Xinyu, Hughes, Elizabeth A., McCann, John C., McAuliffe, John J., Danzer, Steve C., Loepke, Andreas W.

Journal:

Anesthesia & Analgesia

Year:

2013

Language:

english

File:

PDF, 1.04 MB

english, 2013

28

What lessons for clinical practice can be learned from systematic reviews of animal studies? The case of anesthetic neurotoxicity

Loepke, Andreas W., Vutskits, Laszlo

Journal:

Pediatric Anesthesia

Year:

2016

Language:

english

File:

PDF, 112 KB

english, 2016

29

Desflurane Improves Neurologic Outcome after Low-flow Cardiopulmonary Bypass in Newborn Pigs

Loepke, Andreas W., Priestley, Margaret A., Schultz, Steven E., McCann, John, Golden, Jeffrey, Kurth, C. Dean

Journal:

Year:

2002

Language:

english

File:

PDF, 405 KB

english, 2002

30

Glucose and Heart Surgery: Neonates Are Not Just Small Adults

Loepke, Andreas W., Spaeth, James P.

Journal:

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

31

Apoptotic Neuronal Death following Deep Hypothermic Circulatory Arrest in Piglets

Ditsworth, Dara, Priestley, Margaret A., Loepke, Andreas W., Ramamoorthy, Chandra, McCann, John, Staple, Lauren, Kurth, C. Dean

Journal:

Year:

2003

Language:

english

File:

PDF, 832 KB

english, 2003

32

Alpha-stat Induced Alkalosis: Cause of Neuronal Apoptosis after Deep Hypothermic Perfusion: In Reply

Loepke, Andreas W., Ditsworth, Dara, McCann, John C., Dean Kurth, C.

Journal:

Year:

2004

Language:

english

File:

PDF, 307 KB

english, 2004

33

CON: The Toxic Effects of Anesthetics in the Developing Brain: The Clinical Perspective

Loepke, Andreas W., McGowan, Francis X., Soriano, Sulpicio G.

Journal:

Anesthesia & Analgesia

Year:

2008

Language:

english

File:

PDF, 125 KB

english, 2008

34

In Response

Istaphanous, George K., Loepke, Andreas W.

Journal:

Anesthesia & Analgesia

Year:

2013

Language:

english

File:

PDF, 51 KB

english, 2013

35

Comparison of Ropivacaine 0.2% and Lidocaine 0.5% for Intravenous Regional Anesthesia in Volunteers

Hartmannsgruber, Maximilian W. B., Silverman, David G., Halaszynski, Thomas M., Bobart, Vonda, Brull, Sorin J., Wilkerson, Carlos, Loepke, Andreas W., Atanassoff, Peter G.

Journal:

Anesthesia & Analgesia

Year:

1999

Language:

english

File:

PDF, 183 KB

english, 1999

36

Cerebral Oxygen Saturation-Time Threshold for Hypoxic-Ischemic Injury in Piglets

Kurth, C Dean, McCann, John C., Wu, Jun, Miles, Lili, Loepke, Andreas W.

Journal:

Anesthesia & Analgesia

Year:

2009

Language:

english

File:

PDF, 618 KB

english, 2009

37

Con: The Toxic Effects of Anesthetics in the Developing Brain: the Clinical Perspective

Loepke, A.W., McGowan, F.X., Soriano, S.G.

Journal:

Obstetric Anesthesia Digest

Year:

2009

Language:

english

File:

PDF, 68 KB

english, 2009

38

Comparison of dexmedetomidine and chloral hydrate sedation for transthoracic echocardiography in infants and toddlers: a randomized clinical trial

Miller, Jeff, Xue, Bin, Hossain, Md, Zhang, Ma-Zhong, Loepke, Andreas, Kurth, Dean, Anderson, Brian

Journal:

Pediatric Anesthesia

Year:

2016

Language:

english

File:

PDF, 203 KB

english, 2016

39

Beyond Anesthetic Properties: The Effects of Isoflurane on Brain Cell Death, Neurogenesis, and Long-Term Neurocognitive Function

Stratmann, Greg, Sall, Jeffrey W., May, Laura D. V., Loepke, Andreas W., Lee, Michael T.

Journal:

Anesthesia & Analgesia

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

40

Let??s Not Throw the Baby Out With the Bath Water

Soriano, Sulpicio G, Loepke, Andreas W

Journal:

Journal of Neurosurgical Anesthesiology

Year:

2005

Language:

english

File:

PDF, 47 KB

english, 2005

41

Is this your (paediatric patientʼs) brain on (anaesthetic) drugs?

Loepke, Andreas W., Hansen, Tom G.

Journal:

European Journal of Anaesthesiology

Year:

2015

Language:

english

File:

PDF, 80 KB

english, 2015

42

Injury Pattern of the Neonatal Brain After Hypothermic Low-Flow Cardiopulmonary Bypass in a Piglet Model

Loepke, Andreas W., Golden, Jeffrey A., McCann, John C., Kurth, C Dean

Journal:

Anesthesia & Analgesia

Year:

2005

Language:

english

File:

PDF, 876 KB

english, 2005

43

Developmental neurotoxicity of sedatives and anesthetics: A concern for neonatal and pediatric critical care medicine?*

Loepke, Andreas W.

Journal:

Pediatric Critical Care Medicine

Year:

2010

Language:

english

File:

PDF, 281 KB

english, 2010

44

The Physiologic Effects of Isoflurane Anesthesia in Neonatal Mice

Loepke, Andreas W., McCann, John C., Kurth, C Dean, McAuliffe, John J.

Journal:

Anesthesia & Analgesia

Year:

2006

Language:

english

File:

PDF, 468 KB

english, 2006

45

A Combination of Mild Hypothermia and Sevoflurane Affords Long-Term Protection in a Modified Neonatal Mouse Model of Cerebral Hypoxia-Ischemia

Lin, Erica P., Miles, Lili, Hughes, Elizabeth A., McCann, John C., Vorhees, Charles V., McAuliffe, John J., Loepke, Andreas W.

Journal:

Anesthesia & Analgesia

Year:

2014

Language:

english

File:

PDF, 1.26 MB

english, 2014

46

The Effects of Neonatal Isoflurane Exposure in Mice on Brain Cell Viability, Adult Behavior, Learning, and Memory

Loepke, Andreas W., Istaphanous, George K., McAuliffe, John J., Miles, Lili, Hughes, Elizabeth A., McCann, John C., Harlow, Kathryn E., Kurth, C Dean, Williams, Michael T., Vorhees, Charles V., Danzer

Journal:

Anesthesia & Analgesia

Year:

2009

Language:

english

File:

PDF, 2.47 MB

english, 2009

47

Do anesthetics harm the developing human brain? An integrative analysis of animal and human studies

Lin, Erica P., Lee, Jeong-Rim, Lee, Christopher S., Deng, Meng, Loepke, Andreas W.

Journal:

Neurotoxicology and Teratology

Year:

2016

Language:

english

File:

PDF, 998 KB

english, 2016

48

Sedation methods for transthoracic echocardiography in children with Trisomy 21-a retrospective study

Miller, Jeff, Ding, Lili, Spaeth, James, Lam, Jennifer, Paquin, Joanna, Lin, Erica, Divanovic, Allison, Li, Bi Lian, Baskar, Shankar, Loepke, Andreas W., Cravero, Joseph

Journal:

Pediatric Anesthesia

Year:

2017

Language:

english

File:

PDF, 243 KB

english, 2017

49

Biomarkers, Genetics, and Epigenetic Studies to Explore the Neurocognitive Effects of Anesthesia in Children

Levy, Richard J., Herbstman, Julie B., Bosnjak, Zeljko J., Loepke, Andreas W., McGowan, Francis X.

Journal:

Journal of Neurosurgical Anesthesiology

Year:

2016

Language:

english

File:

PDF, 126 KB

english, 2016

50

Long-term Fate Mapping to Assess the Impact of Postnatal Isoflurane Exposure on Hippocampal Progenitor Cell Productivity

Jiang, Y., Tong, D., Hofacer, R. D., Loepke, A. W., Lian, Q., Danzer, S. C.

Journal:

Survey of Anesthesiology

Year:

2017

Language:

english

File:

PDF, 73 KB

english, 2017